Neuropathic pain is a type of chronic pain caused by damage to the nervous system. It is estimated that up to eight percent of the world’s population is affected by this condition. While there are a variety of treatments available, many patients still suffer from the debilitating symptoms of neuropathic pain. This article will provide a comprehensive review of the potential benefits of marijuana as a treatment for neuropathic pain. We will explore the evidence-based research available, discussing the various types of marijuana products and their potential efficacy. Additionally, we will discuss the safety and side effects associated with using marijuana for the management of neuropathic pain. Finally, we will address the implications of using marijuana as a treatment option for neuropathic pain.
What side effects may be associated with using medical marijuana for neuropathic pain?
Common side effects associated with using medical marijuana for neuropathic pain may include dry mouth, nausea, dizziness, increased heart rate, anxiety, drowsiness, sedation, confusion, and temporary memory loss.
Does CBD oil have any impact on neuropathic pain?
Yes, CBD oil has been shown to reduce neuropathic pain in several studies. One study found that CBD oil was effective in reducing neuropathic pain in mice with neuropathic pain caused by chemotherapy. Other studies have found that CBD oil may be helpful in reducing neuropathic pain in humans, as well.
What is the efficacy of medical marijuana for treating neuropathic pain?
Medical marijuana has been found to be an effective treatment for neuropathic pain, a chronic condition which is caused by damage to the peripheral nervous system. A 2017 study found that cannabis-based medicines reduced pain intensity and improved quality of life for patients with neuropathic pain. Furthermore, a recent systematic review found that medical marijuana is effective in reducing short-term pain intensity, improving sleep, and enhancing the overall quality of life for patients with neuropathic pain.
What is the best dosage of marijuana for treating neuropathic pain?
The best dosage of marijuana for treating neuropathic pain will depend on the individual, as each person’s metabolism and body chemistry can vary. Generally, it is recommended to start with a low dose of around 2.5 mg of THC and gradually increase the dose as needed. It is important to discuss the use of marijuana with a doctor to ensure that the dose is appropriate and to avoid any potential negative side effects.
How does medical marijuana compare to other treatments for neuropathic pain?
Medical marijuana has been shown to be a safe and effective treatment option for neuropathic pain. It is often found to be more effective than other treatments for neuropathic pain, such as the use of over-the-counter medications, physical therapy, and nerve blocks. Research has found that medical marijuana can provide relief from neuropathic pain by reducing inflammation and stimulating the endocannabinoid system. In addition, medical marijuana has fewer side effects than many other medications used to treat neuropathic pain.
The research intends to lead to a specific recommendation of an optimal deltatetrahydrocannabinol THC cannabidiol CBD dosage for the treatment of neuropathic pain in a particular subgroup of patients. In addition, it contributes to evidence for the effectiveness of medicinal cannabis. As a clinical pharmacologist, you extract the proven pharmacological components from a plant and do research with it. The researchers will very accurately measure the pharmacodynamics and pharmacokinetics of THC and CBD, the effects of both substances on pain and brain function and how the substances behave in the human body. The Dutch company Echo Pharmaceuticals from Leiden will produce the tablets for the research. The study consists of two parts. The first part of the research will show whether the adverse effects of THC, such as getting high or feeling anxious, can be reduced by administering CBD simultaneously. CBD could have an effect on inflammation, but there is no reason to use CBD as a treatment for inflammatory pain. We already have Ibuprofen for that. It will only become interesting if the adverse effects of THC, such as feelings of anxiety, can be alleviated by administering CBD at the same time. THC 9-tetrahydrocannabinol and CBD cannabidiol are the two most studied active ingredients of the cannabis plant. THC is known for its analgesic effect, but it also causes psychoactive side effects. CBD could lead to pain-relieving effects through other mechanisms. In addition, it is still unclear whether the analgesic effects that some patients experience as a result of CBD use are due to a pharmacological action of CBD, or simply because CBD prevents the metabolism of concomitantly used pain killers. The latter will also be investigated in these studies. The effects on pain in patients will not be investigated until the second part of the study, after the results of the first study are known. The second part of the study will take place among a diverse group of patients with different neuropathic pain conditions. This means that we want to know exactly how the neuropathic pain manifests itself specifically in this group. Do patients have demonstrable nerve damage, do they have a personality disorder, are they depressed, or do they have sleep disorders? All these are variables that we are going to map. Subsequently, the participants in a crossover study will receive placebo for five weeks, and after a wash-out period, they will receive five weeks of cannabinoid treatment or vice versa. Pain will be measured in each treatment period. The first part of the study will start in the spring of , and Groeneveld expects the first results in the summer. The second part of the study with the pain patients will start in the autumn and will last at least two years. Healthy subjects The study consists of two parts. Patients with neuropathic pain conditions The effects on pain in patients will not be investigated until the second part of the study, after the results of the first study are known. A fully standardised product, but with different prices. How come? The important role of pharmacists and medicinal cannabis. Go To. Follow Us. Contact Us. Start typing and press Enter to search.
Jump to navigation. There is a lack of good evidence that any cannabis-derived product works for any chronic neuropathic pain. Neuropathic pain is pain coming from damaged nerves. It is different from pain messages that are carried along healthy nerves from damaged tissue for example, a fall, or cut, or arthritic knee. Neuropathic pain is treated by different medicines to those used for pain from damaged tissue. Several products based on the cannabis plant have been suggested as treatment for pain, including neuropathic pain. These products include inhaled herbal cannabis, and various sprays or tablets containing active cannabis ingredients obtained from the plant, or made synthetically. Some people with neuropathic pain claim that cannabis-based products are effective for them, and that is often highlighted in the media. Study characteristics. In November we searched for clinical trials that used cannabis products to treat conditions with chronic neuropathic pain in adults. We found 16 studies involving people. Studies lasted 2 to 26 weeks. Studies compared different cannabis-based medicines. Ten studies compared an oromucosal mouth spray with a plant-derived combination of tetrahydrocannabinol THC , the principal psychoactive constituent of cannabis, and cannabidiol CBD , an anti-inflammatory ingredient of cannabis, against a fake medication placebo. Two studies each compared inhaled herbal cannabis and cannabis plant-derived THC with placebo, and one study compared a man-made cannabinoid mimicking the effects of THC nabilone with placebo. One study compared nabilone with a pain killer dihydrocodeine. We rated the quality of the evidence from studies using four levels very low, low, moderate, or high.
